Biosystemix Ltd.

Biosystemix Founder Profiles

Dr. Larry D. Greller

Dr. Larry D. Greller is Chief Scientific Officer and Co-Founding Director (together with Dr. Roland Somogyi) of Biosystemix, Ltd. in Kingston, Ontario.  Biosystemix specializes in providing advanced data mining, data analysis, and mathematical modeling solutions to biomedical research customers in the pharmaceutical, biotechnology, academic, and public sectors.  Previously, Dr. Greller was Senior Director of Mathematical Modeling at Molecular Mining Corporation (MMC) in Kingston, Ontario. There he led projects on algorithm development for gene expression analysis commercial software, as well as supervising toxicological and biomedical data mining analyses for customers. His current research interests include the computational reverse engineering of gene and protein interaction networks directly from data. He has over 20 years of broad industrial applied research experience in nonlinear dynamics, mathematical modeling, and the computational detection of high-value patterns in large-scale biological data, including 9 years in scientific computing and mathematical modeling at SmithKline Beecham (SB) Pharmaceuticals R & D (now GSK).  In his capacity at SB as Assistant Director of Bioinformatics Mathematical Biology, he co-developed a variety of mathematical modeling projects for pharmaceuticals research in cancer, blood coagulation, osteoporosis, and gene regulatory networks. Before SB, Greller was at Dupont Central Research and Dupont Merck, Wilmington, Delaware for 5 years. There he focused on chemical oscillations and chaos in hydrocarbon oxidation as well as building neural networks for protein motif detection. Previously, he held academic positions in applied mathematics, computer science, and simulation at the University of Denver and the University of Missouri-Columbia. Dr. Greller received his Ph.D. in mathematical molecular biology from the University of Pennsylvania, an M.S. in Computer & Information Science from Penn’s Moore School of Electrical Engineering, and a B.S. in Physics from Drexel University.

Dr. Roland Somogyi

Roland Somogyi is President and and Co-Founding Director (together with Dr. Larry Greller) of Biosystemix, Ltd., where he is focusing efforts on providing advanced data mining and predictive modeling solutions to pharmaceutical, biotechnology, academic and public research partners.  He has been leading the development of data-driven computational solutions that can solve complex predictive problems directly from the high-throughput genomic measurements and large clinical databases that are populating today’s biomedical research world.  These predictive solutions are critical for the success of cutting-edge efforts in novel target discovery, more efficient screening and toxicological assays, and the enablement of personalized medicine.  Dr. Somogyi has twenty years of experience in academia, government and industry, in the areas of genomics, computational biology and the biophysics of cell signaling.   Previously, he was Chief Scientific Officer at Molecular Mining Corporation (Kingston, Ontario), and has held positions at Incyte Genomics (Palo Alto, California), the National Institutes of Health (NIH; Bethesda, Maryland), and the Pharmacological Institute of the University of Bern (Bern, Switzerland).  As PI at NIH, his group pioneered methods for high-fidelity, high-throughput expression measurements, exploratory data mining & visualization, and network reverse engineering.  Dr. Somogyi is frequently called upon as an invited speaker at international meetings in computational biology and genomics, and has organized a number of conference symposia.  In addition, high-level government committees in both North America and Europe have sought his expertise as an advisor on genomics, bioinformatics and systems biology.  He is currently a member of the Scientific Advisory Board of GNI (Gene Networks International).  Dr. Somogyi holds an M.Sc. in Biology and a Ph.D. in Biophysics and Physiology (Summa cum Laude) from the University of Konstanz (Konstanz, Germany).

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